Revolutionizing Gene Therapy Manufacturing: The Pro10™ Cell Line Enhances Recombinant AAV Production

By Eleanor Harrison Mar27,2024
A Pro10 Cell Line: Proprietary Mammalian Suspension Technology for Scalable rAAV Production

This paper highlights the Pro10™ cell line, a new technology that enhances the efficiency and scalability of recombinant adeno-associated virus (rAAV) production for gene therapy manufacturing. The Pro10™ cell line is a proprietary mammalian suspension technology that enables the scalable and robust production of rAAVs, addressing the challenges associated with large-scale manufacturing in AAV gene therapies.

The Pro10™ cells have been fully characterized and licensed for gene therapy development by various biopharmaceutical companies. Viralgen utilizes these cells as the core of a reliable and scalable rAAV vector manufacturing process. These cells have been specifically optimized for rAAV production and have successfully been scaled up to 2000L, showcasing consistent and reproducible cell growth rates. They have demonstrated similar productivity levels in both small and large-scale bioreactors and are capable of producing various AAV serotypes.

The Pro10™ cells play a critical role in Viralgen’s platform process for manufacturing AAV vectors and have significantly contributed to the production of innovative gene therapies. For more information on the HEK293 derived animal component-free suspension Pro10™ cell line, please access the full PDF detailing its properties and potential benefits for reducing process development time and costs.

By Eleanor Harrison

As a content writer at newseasoning.com, I infuse flavor into words, crafting compelling stories that captivate and inform our audience. With a keen eye for detail and a passion for creativity, I strive to create content that not only engages but also inspires. Whether I'm concocting a savory blog post or whipping up a spicy product description, I pour my heart and soul into every piece I write. Join me on this flavorful journey as we explore the tantalizing world of content creation together.

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